Pimavanserin (Nuplazid, FDA approved to treat Parkinson’s disease psychosis)
Quetiapine (Seroquel)
Clozapine (Clozaril)
Avoid all other typical and atypical antipsychotics
Domperidone (Motilium)
Trimethobenzamide (Tigan)
Ondansetron (Zofran)
Dolasetron (Anzemet)
Granisetron (Kytril)
Prochlormethazine (Compazine)
Metoclopramide (Reglan)
Promethazine (Phenergan)
Droperidol (Inapsine)
Fluoxetine (Prozac)
Sertraline (Zoloft)
Paroxetine (Paxil)
Citalopram (Celexa)
Escitalopram (Lexapro)
Venlafaxine (Effexor)
Amoxapine (Asendin)
Request a consult with the anesthesiologist, surgeon and Parkinson’s doctor to determine best anesthesia given your Parkinson’s symptoms and medications
If patient is taking MAO-B inhibitor such as Selegiline or Rasagiline (Azilect), avoid:
Meperidine (Demerol)
Tramadol (Rybix, Ryzolt, Ultram)
Droperidol (Inapsine)
Methadone (Dolophine, Methadose)
Propoxyphene (Darvon, PP-Cap)
Cyclobenzaprine (Amrix, Fexmid, Flexeril)
Halothane (Fluothane)
Most are safe to use, but narcotic medications may cause confusion/ psychosis and constipation
If patient is taking MAO-B inhibitor such as selegiline or rasagiline (Azilect), avoid meperidine (Demerol)
Reference: Parkinson Foundation Website, available at: www.parkinson.org